Abstract
The objective of present study was to estimate and compare the serum copper level in patients with benign prostatic hypertrophy and prostate carcinoma and their correlation with serum acid phosphatase. Prostatic acid phosphatase for Group A was 2.28 ± 0.99, for Group B 16.03 ± 5.89 and for Group c 46.43 ± 6.22 U/L, respectively. Highly significant P- value of 0.0001 was noted among all the 3 groups; A, B and C. Serum copper levels in Group A 106.88 ± 19.28, Group B 104.29 ± 17.40 and Group C 92.88 ± 11.28µg/L, respectively. P value between groups A vs B, A vs C and B vs C were noted as 0.052, 0.001 and 0.022, respectively. Serum copper was reduced in group B compared to A, but P value showed no significant difference (p=0.052). However, A vs C and B vs C showed statistically significant differences. The present study reports the raised prostatic acid phosphatase, and decreased serum copper levels in carcinoma of prostate gland indicating their diagnostic and prognostic significance.
