In the present study we investigated the effectiveness of seed priming and seed pelleting with Prosopis juliflora (Sw) Dc. parts on plant growth and suppression of root rot fungi, Fusarium spp., Rhizoctonia solani and Macrophomina phaseolina infestation under field condition. Seed pelleting with P. juliflora leaves powder showed significant (P increase in both growth parameter and plants yield. Whereas seed priming resulted in complete suppression of root rot fungi R. solani and M. phaseolina. Our study suggests that seed pelleting is the best strategy over seed priming because it protects seeds from soil borne pathogens.