Vitamin D binding protein (VDBP) gene polymorphisms have been found associated with risk of developing Type 2 diabetes mellitus (T2DM) in a Pakistani population. This study aims to evaluate VDBP expression in T2DM patients as plausible alteration in its expression might contribute to vitamin D deficiency.We analyzed VDBP expressionin T2DM patients and healthy controls by 2-DE followed by its validation via western blotting. In SilicoPPI analysis was performed to evaluate role of VDBP and its interacting proteins with disease pathology.2-DE analysis revealed significant upregulated expression of VDBP in T2DM patients compared with controls (Fold change >1.7, *p
Khalida Iqbal, Ayesha Khan, Nikhat Ahmed. (2018) DIFFERENTIAL EXPRESSION OF VITAMIN D BINDING PROTEIN IN TYPE 2 DIABETES MELLITUS PATIENTS, , Volume 15, Issue 3.
