Abstract
Hydatidosis or Echinococcosis is caused by a parasitic cestode, Echinococcus (Rudolphi, 1807) with a life cycle having sheep and cattles as an intermediate and canines as a definitive host. Humans, if harbor, is the dead end host. It serves as an important zoonosis in areas where there is close association between humans and domestic livestock. This is a retrospective observative study conferring pathological features of hydatid infection during 2013 in major tertiary care hospitals in Karachi. This seminal study provides regarding infectivity of hydatidosis in Karachi population. Study revealed increasing prevalence of infection in age group between 21-40 years with similar proportion in male and females. Liver and lungs are the most commonly involved organs whereas kidney, spleen, lower limb, breast and other organs are rarely involved.