Abstract
Pseudomonas aeruginosa has become an important cause of infections for example bacteremia, urinary tract infections and pneumonia etc. Antibiotic resistance rates in Pseudomonas aeruginosa are increasing worldwide. For treatment of infections caused by P. aeruginosa, beta-lactam and aminoglycoside antibiotics are widely used. The present study was undertaken to assess the current level of susceptibility to the most common antipseudomonal antibiotics (meropenem, timethoprim-sulfamethoxazole, piperacillin/tazobactum, amikacin, ciprofloxacin, gentamicin, polymyxin B, aztreonam, cefoperazone, azithromycin, ampicillin, amoxicillin/clavulanic acid and ceftazidime) against different strains of P. aeruginosa isolated from pus, water, blood, sputum, urine, ear swab, throat swab and fluids. The antibiotic sensitivity test of each isolate was performed by the Kirby-Bauser disc diffusion method as per recommendation of National Committee for Clinical Laboratory Standards. Among all tested antibiotics aztreonam, amoxicillin/clavulanic acid and ampicillin were found to be the most effective antibiotics against P. aeruginosa with the resistant rates of 1.0, 2.1, and 2.4 % respectively. The highest resistant rates were observed against ceftazidime (39.7%), gentamicin (33.9%) and ciprofloxacin (29.5%).
