The crude extract of Myrica. nagi bark was tested for its analgesic activity by writhing and hot plate methods and its antiinflammatory activity by formalin test method in Swiss albino mice. In analgesic activity assessment by writhing test, the extract showed effectiveness at 300mg/kg (77.24 and 58.88% inhibition respectively) in both early and late phases in comparison with 500mg/kg dose which showed non-significant activity (33.56 and 22.22% inhibition) in both phases. Standard drug aspirin showed 41.83% inhibition of first phase and 74.07% inhibition of second phase. M. nagi bark also exhibited negligible analgesic activity in comparison with standard drug aspirin. It showed significant reduction in tail flicking and biting response. M. nagi bark @ 300 and 500 mg/kg dose showed 40.0 and 11.81 and 41.64 and 6.36% of inhibition of licking and bitting respectively at early and late phases.
