Abstract
The weight reducing herbal drug, Mehzileen, was administered orally to common rabbits Oryctolagus cuniculus in a daily dose of 30 mg for 27 days. Blood samples drawn from the animals on day 0, 3, 7, 10 and 27, were used to measure plasma electrolytes. The results showed significant (p< 0.05) elevation in mean concentrations of sodium and potassium. Calcium concentration initially showed a rise then declined after day 10 of drug administration. The major ingredients of the herbal drug used are tonic, laxatives and diuretic, severely affecting digestive system and kidneys, therefore, may result in electrolytes imbalance.