Abstract
Ipomoea pes-caprae (L.) R. Br., is a herb traditionally used by the tribes of kerala as a single drug remedy to treat painful conditions like headache, swellings, poisonous stings and snake bites. The ethanolic extract of Ipomoea pes-caprae , Family: (Convolvulaceae) was evaluated for analgesic property using plate reaction time. I. pes-caprae extract showed a dose dependent significant reduction of the number of writhes (P0.05).The preliminary studies shows that the ethanolic leaf extract of I. pes-caprae has significant analgesic activity and needs further investigations.