Abstract
Many adverse health effects have been reported with the use of tobacco (smokeless) in populations, including CVDs, buccal cavity cancers, soft tissue lesions of mouth and gum recession. The purpose of Present study is to evaluate and compare specific cardiovascular risk factors in individuals using smoked and smokeless tobacco products. Total of 220 age matched , male subjects were selected to participate in the study, who had a history of smoking or tobacco chewing or both. Base line history was collected through a questionnaire and anticoagulated venous blood samples were collected and analyzed for plasma glucose, lipid profile and blood glutathione levels. Results showed that in Pakistan middle class socioeconomic group has high prevalence of both forms of tobacco use. Mean BMI and prevalence of obesity were low in three tobacco groups. Systolic and diastolic BP were high in tobacco users but prevalence of hypertension was more in subjects using both forms of tobacco. Marked lipid profile and glutathione variations were present in all tobacco users. Plasma glucose concentrations also showed a non significant increase in three experimental groups as compared to controls.
