Eighteen treatment-resistant schizophrenic patients were assigned to three equal groups: one group was given clozapine; one group was treated with ECT; and one group was treated with the combination of clozapine and ECT. The treatment response was evaluated using the PANSS criteria, and the data were analyzed with ANOVA. Combination therapy was superior to single modality therapy. The reduction of PANSS scores was 46% in the clozapine group, 40% in the ECT groups, and 71% in the combination group; the difference between the combination group and the other groups was statistically significant (P
M.A. Mohseni Bandpei, A.R. Khalilian. (2007) COMPARATIVE STUDY OF CLOZAPINE, ELECTROSHOCK (ECT), AND THE COMBINATION OF ECT WITH CLOZAPINE IN TREATMENT-RESISTANT SCHIZOPHRENIC PATIENTS, , Volume 4, Issue 2&3.
