Psidium guajava belongs to the family of Myrtaceae, is widely grown in Sistan and Balochistan provinces in the South of Iran. P.
guajava is known in folk medicine as a medicinal plant that used as hypotensive and anti-diabetic. In the present studies aqueous
green leaf extract of P. guajava (400 mg/kg) showed a strong glucose lowering effect after oral administration in rats. The decrease of
glycemia has reached to 30% of the control value 2 h after glucose loading. The amount of glucose absorbed in a segment jejunum in
situ was 9.32±0.32 mg in the presence of tea extract as compared to control (14.55 ±045 mg ) during 2 h (P<0.05). The results indicate
that aqueous extract of tea has a significant anti hyperglycemic effect that may be caused in part by the reduction of intestinal glucose
absorption.
