Abstract
Many factors are associated with decreased risk for coronary heart disease. One of these main factors is the distribution of plasma cholesterol over low density and high density lipoproteins (LDLs & HDLs). This can be modified by changing the source and amount of fats and oils in the diet. Therefore the main purpose of this investigation is to assess the effects of three dietary high fat diets on distribution of plasma lipoproteins in rabbit. Twenty male New Zealand White rabbits aged 4.5 months were randomly divided into four different groups. To each group was assigned a total of 5 rabbits and dietary feeding was commenced 15 days later at the age of four months after the rabbits had been acclimatised to their new environment in the animal experimental unit. The rabbits were fed for a total of two months a 10% (w/w) high fat diet containing the dietary oils I. Fed basal diet on commercial diet (CO), II. Fed basal diet contains 10% batterfat-ghee-oil (GH), III. Fed basal diet with 10% hydrogenated vegetable fat (HD) & IV. Fed basal diet with 10% unsaturated sunflower oil (SU). At the end of two months feeding the rabbits fasted overnight and had their blood collected by heart puncture. Blood samples were collected for measuring and comparison of the concentrations of HDL and LDL cholesterol, total cholesterol and triglycerides inserum. Results show that Plasma lipids and lipoproteins are affected by type of dietary fats and it seems that the impact of the hydrogenated oil is higher than others, and it increased significantly TG,HDL-chol, VLDL-chol respectively (P
