Abstract
Purpose: To study the effect of short-term use of oral contraceptive pills on
intra-ocular pressures of women of childbearing age.
Study Design: Observational case control study.
Place and Duration of Study: The study was conducted at Arif memorial
teaching hospital and Allied hospital Faisalabad from October 2017 to March
2018.
Material and Methods: There were 100 female subjects, who were divided into
two groups of 50 each. Group A, included females, who had been taking oral
contraceptive pills (OCP) for more than 6 months and less than 36 months.
Group B, included 50 age-matched controls, who had never used OCP.
Ophthalmic and systemic history was taken. Careful Slit lamp examination was
performed and intraocular pressures (IOP) were measured using Goldman
Applanation tonometer. Fundus examination was done to rule out any posterior
segment disease. We compared the intra ocular pressures between the two
groups by using Student t test.
Results: Average age was 29.16 in group A and 27.74 years in group B. Average
duration of using OCP was 14.9 months. Mean IOP in right eye was 13.08 ± 1.41
mm of Hg and 13.34 ± 1.27 mm of Hg in left eye in Group A. While, mean IOP in
right eye was 11.72 ± 1.35 mm of Hg and in left eye was 11.92 ± 1.3 mm of Hg
in controls. Significant difference was noted between the IOP of OCP group and
controls. (p = 0.000).
Conclusion: OCP significantly increases IOP even when used for short time
period.
Tayyaba Gul Malik, Hina Nadeem, Eiman Ayesha, Rabail Alam. (2019) Effect of Short-term Use of Oral Contraceptive Pills on Intraocular Pressure, Pakistan Journal of Ophthalmology, Volume 35, Issue 3.
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