Abstract
A retrospective study was conducted to find the incidence of carcinoma of gall bladder. Data were collected from the patients admitted with cholelithiasis in surgical units of different hospitals of Karachi during the year July 2002 to June 2004. All of them underwent Cholecystectomies. Out of 153 patients, 62 (40.5 %) were male and 91 (59.5 %) were females with mean age of 40 and 54 years respectively. The patients were admitted with commonest clinical presentation of upper abdominal pain, dyspepsia and palpable gall bladder. Liver function tests were altered in most of the cases (72.5 %). Ultrasonography was carried out on all patients. Results showed cholelithiasis in 87.6 % cases, wall thickening 90.2 %, wall irregularity 32.7 % and CBD dilatation in 39.2 % with and without stones. Histopathology of most of the above cases revealed inflammatory changes and patients were diagnosed with adenocarcinoma of gall bladder. Follow up was not possible due to lack of coordination between surgical unit and pathology department. The incidence of neoplasia on routine histopathology after cholecystectomy for cholelithiasis was found to be as 8.5 %.

S. M. Hasan, F. Imtiaz, S. M. Hasan, S.A.H. Zaidi. (2005) FREQUENCY OF GALL BLADDER CARCINOMA ON ROUTINE HISTOPATHOLOGY AFTER CHOLECYSTECTOMY, , Volume 2, Issue 1.
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