Abstract
Purpose: To compare the post operative inflammatory pattern after
phacoemulsification in patients receiving intra-cameral injection of ceftazidime
and cefuroxime per-operatively for the prevention of post-operative
endophthalmitis.
Study Design: Quasi experimental study.
Place and Duration of Study: Ophthalmology Department Unit-1, Lahore
General Hospital, Lahore from November 2016 to March 2018.
Material and Methods: Patients undergoing phacoemulsification with
intraocular lens implantation were divided into 2 groups by convenient sampling.
Group A received Cefuroxime and group B received Ceftazidime both as 1
mg/0.1ml intra-cameral injections at the end of the routine surgery. The patients
were examined pre and post operatively on slit lamp and the number of cells in
the anterior chamber (A/C) were counted on first day, first week and 6 weeks
after surgery.
Results: Out of 260 patients there were 130 in each group. On the first postoperative day in group A there were grade 1 cells in A/C in 22 patients, grade 2
in 93 patients, grade 3 in 14 patients and Grade 4 in 1 patient. In group B there
were grade 1 cells in A/C in 11 patients, grade 2 in 96 patients, grade 3 in 20
patients and grade 4 in 3 patients. After one week, in group A, cell counts were
grade 0 in 27 patients while in group B, cell counts were grade 0 in 23 patients.
After 6 weeks no patient in any group showed any activity in the anterior
chamber.
Conclusion: There is little difference in post operative inflammatory pattern of
intracameral ceftazidime antibiotic prophylaxis as compared to intracameral
cefuroxime.
Muhammad Moin, Arooj Amjad, Sameer Nagi. (2019) Comparison of Post-operative Inflammatory Pattern between Intracameral Ceftazidime and Cefuroxime Used for the Prevention of Post-operative Endophthalmitis, Pakistan Journal of Ophthalmology, Volume 35, Issue 3.
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