Abstract
Purpose: To study Human Immunodeficiency Virus (HIV) / Acquired
Immunodeficiency Syndrome (AIDS) related ocular manifestations in patients
undergoing highly active anti-retroviral therapy (HAART) in Jeddah, Saudi
Arabia.
Study Design: Descriptive study.
Place and Duration of Study: Ophthalmology Clinic of East Jeddah Hospital.
Kingdom of Saudi Arabia, during 2016-2017.
Material and Methods: All patients who were positive for HIV/AIDS and taking
highly active anti-retroviral therapy seen in the department of Infectious diseases
of our hospital were included in the study. The data for the 47 HIV/AIDS positive
referrals was collected from the Infectious Diseases Department by taking
history, clinical examinations, and laboratory investigations. The
ophthalmological examination consisted of adnexal examination, best corrected
visual acuity, Intraocular pressure (IOP), anterior and posterior segment
examination, B-scan and MRI.
Results: There were 47 patients included in the study. There was one patient
each of retinal necrosis, anterior uveitis “and” neovascular glaucoma, pterygium,
sixth nerve palsy, bacterial conjunctivitis and adenoviral conjunctivitis. Two
cases presented with HIV microangiopathy, blepharitis, cortical blindness after
brain abscess, herpes infection, Kaposi sarcoma and cytomegalovirus (CMV)
retinitis. Three patients presented with meningitis and six with dry eyes. Eight
patients presented with cataracts and ten with refractive errors tuberculosis.
Conclusion: Ocular manifestations of HIV infection are relatively infrequent in
patients on HAART as this has reduced the HIV-related complications in
ophthalmology.
Muhammad Abdul Rehman Akram, Mazen Ahmed Alzahrani, Asim Mahmood, Thamer Basodan, Eman Oudah Alghamdi, Ali Alansari. (2019) Ocular Manifestations in HIV/AIDS Patients Undergoing Highly Active Antiretroviral Therapy, Pakistan Journal of Ophthalmology, Volume 35, Issue 3.
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