Abstract
The present study was designed to see the effect of bis 3- Azophenyl-4-Hydroxy -6-Methyl-2-H-Pyran-2-one iron (II) (complex) in (DMBA), 7, 12 Dimethylbenz [a] Anthracene followed by 12-OTetradecanoyl-phorbal-13-Acetate, (TPA) induced tumours on the skin of albino rats. Eighty albino rats were divided into four groups. Groups A & B were used as control. DMBA was given to group C 100μg/ml as single dose along with @ TPA 10μg/ml in acetone twice a week. In-group D all the chemical carcinogens (DMBA & TPA) were applied locally in the same dose, route and schedule, after the induction of skin cancer, the complex (bis 3-Azophenyl-4-Hydroxy-6-Methyl-2H-Pyran-2-one iron (II) was applied by the same route followed by study of therapeutic role.
SAMINA SHAHID , JAVAID IQBAL , MUHAMMAD SHARIF MUGHAL. (2006) CHEMOTHERAPEUTIC ROLE OF BIS 3-AZOPHENYL4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE IRON (II) IN CHEMICALLY INDUCED SKIN CANCER IN ALBINO RATS, Punjab University Journal of Zoology, Volume 21, Issue (1&2).
-
Views
435 -
Downloads
49
