Abstract
-111 organophosphorous insecticide. methamidiThos was tested tar its enthi-votiimeir, and t....ratogenceity in mice. 1)ill'ererit sublethal doses of the insecticide i.e.. 1: 5. 25 and 50". of 1.1). comprising 1.125. 2.25 and 4.5 Itg g lily acre prepared by dissolving it in water in web in that Cad) U. I 1111 of the solution ,tnit,ots, desired eini,entraiiiiii These doses were administered oralle to the prepaid mire on different .y,est.iiiim The lauses Were do, 15 of gestation. Fetal llotb ocight :Ind crown runip length decreased in higher doses and longer exposure groups, lorphometric studies of these fetuses aware also done which were comprised of the ineiraireinents of size of brain. eye. eat. snout. lower blahs and upper limbs. Sizes of these organs deereased siptilleantly (P 0.001) in higher dose groups. Some morphological abramnalities including brain defects. dermal luiemorrhagic patche, limb detects and a high rate or resorptions were Boned in all dose groups. The present stud) indicates that concentrations of this insecticide used are highly dangerous !Ur 111011S4 development which may he equally hatyntid For human too.
ASMATULLAH , Rabia Hanif. (2000.) TERATOGENIC EFFECTS OF SUBLETHAL DOSES OF METHAMIDOPHOS IN MICE, Punjab University Journal of Zoology, Volume 15, Issue .
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