Splenic and cell culture haemorrhagic enteritis (HE) vaccines were administered to separate groups of 4-week old commercial and specific-pathogen-free (SPF) poults. SPF poults receiving both vaccines seroconverted and were protected against virulent HEV challenge. In commercial birds, antibody response to splenic vaccine was significantly higher (P<0.05) than that to cell culture vaccine. Moreover, the protection provided by splenic vaccine was 97% as compared to 61% by cell culture vaccine. The results of this study indicate that in 4-week-old poults, splenic vaccine provided greater seroconversion and better protection than cell culture vaccine.
Iftikhar Hussaln, Kakambi V. Nagaraja, John A. Newman. (1993) EFFICACY OF SPLENIC AND CELL CULTURE HAEMORRHAGIC ENTERITIS VACCINES IN COMMERCIAL AND SPECIFIC-PATHOGEN-FREE TURKEYS, , Volume 30, Issue 4.
