Abstract
An experiment was conducted to compare haematological changes in dogs associated with two isolates of Ehrlich& can% ode which occurs predominantly in lymphocytee and the other found in neatrophils and eosineplails. The study included complete hemegrams (hematocrit, haemoglobin, crthoeytess retioulonytea and total and differential leukocytes). From ilia haematological data. it was concluded that the disease produced by these two isolates of E. earthy differed from each other largely in degree of severity. The neutrcpbilic isolate produced a very mild disorder as compared to the sev re Weiss characterized by anaemia and leukopenia produced by the lympbocytic isolate. Anaemia and leukopenia were not seen in pups infected with rieutrophilio liolate, 'There Ia a stro.ng evidence that the anaemfa in the former case_is due to the severe bone marrow depression. In the latter case !Amato. poietic capabilities were not effected.
INTRODUCTION
Canine eltrIichiosis is a febrile debilitating disease of dogs characterised by anaemia and other sigas. Two strains or Ehrlich& c anis i.e. lymphoeytio !isolate in which the organism as a morula is found predominantly in the cytnplasm or lymphocytes and monocytes and in contrast morulae of Peutorphilic isolate have been found exclusively in neutrophiIsi oecaionally is eosinoph.iis and never in other leukocytes (Ewing of igl„ 1963; Ewing of ar..1971 and Hayat et al., 1972), The ucutrophilic strain was isolated from Arkansas and Oklahoma and prod need a milder form of canine ehrlichios;s than the Oklahoma isolate found in 1962 (Ewing a1 al., 1971; Hayit of at., 1972; Hayat, 1973 acrd Hayat and Ewing 1973), The olinical and haernatologic changes associated with canine ehilichiosis
