Abstract
The effects of an organophosphorus insecticide, methamidophos were evaluated in pregnant mice and developing fetuses. To calculate LD50 values for pregnant mothers and developing fetuses different concentrations (5 to 20 ti.g/g BW) of the insecticide were given orally to pregnant mothers on day 6 of gestation. The Mothers were watched after the dose administration up to 24 hours. The dose of 15 and 20 .i.g/g- • BW proved 100% mother lethal. The mothers that survived for 24 hours after dose administration were found recovered from insecticide's toxic effects as the usual symptoms of eye, oral and anal secretions and limb weakness subsided. The LD50 values for mothers were turned out 9 ag/g BW. The fetuses from mothers survived =after 24 hours of treatment were recovered on day 15 of gestation. Dead fetuses were noted and were fixed in Bouin's fixative. The 1,1350 value for fetus was calculated as 8.2 1.4g BW of mother
ASMATULLAH , TAYYBA ASLAM. (1999) TOXICITY OF METHAMIDOPHOS IN PREGNANT MICE AND DEVELOPING FETUSES , Punjab University Journal of Zoology, Volume 14, Issue 1.
-
Views
460 -
Downloads
58
