Objective: To determine the frequency of candiduria in children and adolescents attending a healthcare facility in Kabul and to analyze antifungal susceptibility of Candida isolates. Study Design: A cross-sectional descriptive study. Place and Duration of Study: French Medical Institute for Mothers and Children Kabul from Jan 2012 to Dec 2017 Material and Methods: The urine samples of patients between ages of neonates to 18 years were examined microscopically and cultured on CLED and CHROMagar Candida plates incubated at 37°C and 30°C for 24-48 hours. Identification of Candida species was made by germ tube test and chromogenic reaction on differential media. The susceptibility was evaluated for common antifungals. Results: Of total 21,455 urine samples, 669 (3.12%) showed candiduria; 391 (58.45%) due to C. albicans and 278 (41.55%) nonalbicans Candida. Majority of isolates showed high resistance to many antifungal drugs. Least resistance was observed against amphotericin B and ketoconazole. Conclusion: Candida albicans remained the predominant source of candiduria in our patients. The candiduria must not be ignored as it may be a sign of systemic candidiasis.
Tariq Mahmud Tariq, . (2020) Rising Frequency of Candiduria in Afghan Children and Adolescents: A Study Carried Out At a Tertiary Healthcare Facility in Kabul, , Volume 44, Issue 3.
