Abstract
Background: Smoking is one of the most important yet modifiable risk factors for incidence, morbidity, recurrence and mortality from PulmonaryKoch’s or tuberculosis. This study attempted to demonstrate the association between smoking and recurrence risk of PulmonaryKoch’s in Pakistani male population.Methods: This case control study wasconducted at Federal Government Tuberculosis Hospital, Rawalpindi from 2015 to 2016. It included 332 study participants;166recurrent cases of Pulmonary Tuberculosis within two years of completion of Anti-tuberculous therapy (ATT)and 166 non-recurrent controls. Smoking status of all study participants was assessed. Results:Amongst 166 cases of recurrence, 75 (63.6%) had continued smoking after ATT compared to 43 (36.4%) controls who continued smoking (p-value 0.00, OR=2.35,95% CI=1.48to3.74,NNH=4.75).Highly statistically significant associations of recurrence were observed with smoking>10 years (p-value 0.00, OR=3.67,CI=1.55–8.71 NNH=4.75) and if ever smoked in life (p-value 0.00,OR=2.05,CI=1.32–3.19,NNH=5.61). Mean duration of smoking in cases (12.37±8.72 years) was statistically different from controls (9.54±7.01 years), with p-value of 0.04.Conclusion: There is strong association of recurrence of Pulmonary Kochs with continuation of smokingwithin 2 years of completion of ATT, with ever smoking in life and smoking >10 years in life.
Dr Muhammad Mujeeb, Muhammad Mujeeb Khan, Faiza Aslam*,, Sundas Abbas, Qurrat-ul-ain Elahi. (2016) ASSOCIATION OF SMOKING WITH RECURRENCE OF PULMONARY KOCHS; AFTER COMPLETION OF ANTITUBERCULOUS TREATMENT, JOURNAL OF AYUB MEDICAL COLLEGE ABBOTTABAD, Volume 28, Issue 4.
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