Abstract
Objective: To compare the lipid profile, specifically
LDL levels, in ischemic and hemorrhagic stroke
patients presenting at Pak Emirates Military Hospital,
Methodology: This comparative cross-sectional study
was conducted at Neurology department of Military
hospital, Rawalpindi from January to March 2021 and
included 100 patients with acute stroke. Any patient
with head injury or on lipid lowering therapy was
excluded from study. Definitive diagnosis was made
after thorough examination and CT scan of brain.
Samples of serum were taken after 8 hours of
overnight fasting following admission and were
analyzed using enzymatic colorimetric method for
lipid profile. SPSS version 23 was used for statistical
analysis.
Results: Among 100 patients, 69 were male and 31
females. Age ranged from 38 to 90 years (mean 66.4 ±
11). Among study participants, 62 patients had
ischemic stroke where as 38 patients were categorized
as hemorrhagic stroke. Majority of study participants
had hypertension and diabetes mellitus as risk factors.
Out of 62 patients with ischemic stroke, 17 patients
had increased total cholesterol levels in the serum with
the mean being 4.5 ± 1.2 mmol/L.
Conclusion: Significant association was found
between total cholesterol, LDL, Triglycerides levels
and stroke. Lipid abnormalities occurred in higher
frequency in patients of ischemic stroke as compared
to those with hemorrhagic stroke.
Keywords: Stroke, ischemic, hemorrhagic, LDL, total
cholesterol, triglycerides, diabetes mellitus,
hypertension.
