Abstract
Objective: To explore the impacts of Chemotherapy,
Radiotherapy and Radioactive Iodine Ablation (RAI)
on symptomatology before and after treatment of
Thyroid cancer (TC) patients at Nuclear Institute of
Medicine and Radiotherapy (NIMRA) Jamshoro and
Larkana Institute of Nuclear Medicine and
Radiotherapy (LINAR), Larkana, Pakistan.
Methodology: The study included 174 thyroid cancer
(TC) patients and 174 controls with age and gender
matched having negative personal or family history of
any cancer or other chronic illness. Both groups before
and after treated thyroid cancer patients were
interviewed through a standard questionnaire
regarding the association and impacts of undesirable
consequences of chemotherapy, radiotherapy and RAI
ablation upon various symptomatology.
Results: Before and after treatment, there was variety
of symptomatology found which badly disturbed the
patients. The effects of radiotherapy were not
considerable outcomes of RAI ablation occurred and
disturbed a lot, although most of them were reversible
while the chemotherapy results were very serious and
troubling.
Conclusion: Radiotherapy and chemotherapy
improved symptomatology in TC patients. In post
radio and chemo therapy, present study revealed
positive changes in the disease associated outcome.
Keywords: Thyroid cancer, radiotherapy,
chemotherapy.
