Abstract
Objective: To determine frequency of common
bacteria causing urinary tract infection (UTI) among
toilet-trained children and their antimicrobial
susceptibility pattern.
Methodology: This descriptive cross sectional study
was completed from October 2020 to March 2021 at
pathology unit of Sahara Medical College, Narowal. It
included 193 toilet-trained children with culture
positive UTI. Demographic details like gender, age,
residential area, and clinical findings along with
isolated microorganism and antimicrobial sensitivity
pattern were recorded. Mid-stream urinary samples
were collected and sent to institutional laboratory for
urine analysis, culture and antimicrobial sensitivity
patterns.
Results: Out of 193 children, there were 108 (54%)
female and 91 (47.2%) male. Mean age was 10.56 ±
3.82 years (range 6 – 14). There were 107 (55.4%)
children above 10 years of age and 122 (63.2%)
belonged to rural areas. Most common bacteria
isolated was E. coli in 155 (80.3%) cases.
Antimicrobials having highest sensitivity against the
causative bacteria include imipenem and meropenem
189 (97.9%), piperacillin tazobactam 187 (96.9%),
amikacin 185 (95.8%), fosfomycin 184 (95.3%),
gentamycin 178 (92.2%) and sulzone 171 (88.6%).
Conclusion: E. Coli was the commonest bacteria
causing UTI among toilet trained children.
Antimicrobials with highest sensitivity against the
causative organisms include imipenem, meropenem,
piperacillin tazobactam, amikacin and fosfomycin.
Keywords: Urinary tract infection, gram-negative
bacteria, E.coli, toilet-trained children.
