Abstract
Objective: To determine frequency of common bacteria causing urinary tract infection (UTI) among toilet-trained children and their antimicrobial susceptibility pattern. Methodology: This descriptive cross sectional study was completed from October 2020 to March 2021 at pathology unit of Sahara Medical College, Narowal. It included 193 toilet-trained children with culture positive UTI. Demographic details like gender, age, residential area, and clinical findings along with isolated microorganism and antimicrobial sensitivity pattern were recorded. Mid-stream urinary samples were collected and sent to institutional laboratory for urine analysis, culture and antimicrobial sensitivity patterns. Results: Out of 193 children, there were 108 (54%) female and 91 (47.2%) male. Mean age was 10.56 ± 3.82 years (range 6 – 14). There were 107 (55.4%) children above 10 years of age and 122 (63.2%) belonged to rural areas. Most common bacteria isolated was E. coli in 155 (80.3%) cases. Antimicrobials having highest sensitivity against the causative bacteria include imipenem and meropenem 189 (97.9%), piperacillin tazobactam 187 (96.9%), amikacin 185 (95.8%), fosfomycin 184 (95.3%), gentamycin 178 (92.2%) and sulzone 171 (88.6%). Conclusion: E. Coli was the commonest bacteria causing UTI among toilet trained children. Antimicrobials with highest sensitivity against the causative organisms include imipenem, meropenem, piperacillin tazobactam, amikacin and fosfomycin. Keywords: Urinary tract infection, gram-negative bacteria, E.coli, toilet-trained children.

Saeeda Nabat-ul-Hassan, Sadia Zia, Usman Ali. (2022) Microorganism causing urinary tract infection among children and their antimicrobial susceptibility patterns, , Volume 47, Issue 1.
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