Abstract
Objective: To compare anxiety and depression
between proctitis to extensive colitis patients and
healthy controls across gender.
Methodology: Five (5) (Ulcerative Colitis) X 2
(Gender) multifactorial cross-sectional designswere
adopted. Data were collected form Gastroenterology
Department of Mayo Hospital during January to June
2021. Out of 600 participants, we purposively sampled
300 patients suffering from different stages of
Ulcerative Colitis including 36 (12%) proctitis, 40
(13.3%) proctosigmoiditis, 124 (41.3%) left sided and
100 (33.3%) extensive colitis patients. A healthy
control group of 300 individuals living in community
were purposively selected for comparison.
Demographic information form along Beck Anxiety
Inventory, Beck Depression Inventory were used to
collect data which was analysed through SPSS 23.
Results: MANOVA examined gender and Ulcerative
Colitis for anxiety and depression as dependent
variables and found Ulcerative Colitis (Wilks'
Lambda = .01, F (8) = 375.61, p = .001) and gender
(Wilks' Lambda = .70, F (2) = 31.45, p = .001) were
significant, however the interaction was not. ANOVA
for Ulcerative Colitis revealed significant effects for
anxiety, F (4,590) = 460.36, p = .001, η2 =. 92 and
depression F (4,590) = 3823.89, p = .001, η2 = .99.
Anxiety and depression were significantly higher in
extensive colitis patients followed by distal,
proctosigmoiditis, proctitis and controls. Women had
more anxiety and depression than men.However, the
averages reached to severe anxiety and depression in
stage 4 male and female patients.
Conclusion: Medical professionals should assess
anxiety and depression as integral parts of Ulcerative
Colitis assay and refer distal and extensive colitis
patients to mental health clinicians to cope better with
their physical and psychological issues associated with
the ailment.
Keywords: Proctitis, proctosigmoiditis, distal colitis,
extensive colitis, anxiety, depression
