Abstract
Purpose: To measure and analyze thickness of retinal nerve fiber layer usingOptical Coherence Tomography (OCT).Material and Methods: This study was conducted in ophthalmology departmentPNS Shifa, Karachi. From March 2013 to Jan 2015 for 23 months. A total of 350glaucoma suspect patients were selected. A detailed history of ocular orsystemic diseases was taken. Intraocular pressure (IOP) was measured usingGoldmann Applanation tonometer. Optical Coherence Tomography (OCT)images were taken using Heidelberg HRA + OCT Spectralis machine.Results: Patients with a mean age of 35 ± 12 years were included. Out of 350patients, 140 (40%) patients were female and 210 (60%) were male. Mean IOPwas 25 ± 5 mm Hg, mode was 23 mm Hg and median 26 mm Hg. Out of these350 suspects, only 28 patients were found to have nerve fiber layer thicknessoutside the normal limits i.e. decreased in half a quadrants or more.Conclusion: Ocular coherence tomography nerve fiber layer thickness analysisis a quick and effective method to diagnose early and borderline cases ofglaucoma.Key Words: Optical coherence tomography (OCT), retinal nerve fiber layer(RNFL), glaucoma, intraocular pressure (IOP).

Abdul Majeed Malik, Saima Irum, Kashif Ali. (2015) Early Detection of Primary Open Angle Glaucoma by Using Optical Coherence Tomography, Pakistan Journal of Ophthalmology, Volume 31, Issue 2.
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