Abstract
Purpose: To evaluate the safety and efficacy of riboflavin – ultraviolet type A light rays induced cross-linking of corneal collagen in keratoconus. Material and Methods: Forty cases of collagen cross-linking were studied retrospectively. Preoperative examination included uncorrected and bestcorrected visual acuity, refraction, slit-lamp, fundoscopy and orbscan. Routine cross-linking procedure was performed. Postoperatively, a bandage contact lens was applied which was removed on the 5th day. Subsequent postoperative examinations were performed monthly for six months. Results: Forty cases completed six months of follow up. There were 21 males and 19 females in the study. The age range was 16-32 years. In the six months study, 13 out of 40 cases showed improvement of un-corrected visual acuity by one line and 15 out of 40 had improvement by 2 or more lines. Only two eyes out of 40 (5%) lost 2 or more lines of uncorrected visual acuity. Keratometric improvement was seen in 22.5%. 65% showed keratometric stability while progression was seen in 12.5%. Conclusion: Collagen cross – linking is a safe and effective procedure in halting the progression of keratoconus.

Aneeq Ullah Baig Mirza, Yasir Iqbal, Mirza Inamul Haq. (2012) Visual and Keratometric Results after Corneal Collagen Cross Linking in Keratoconus, Pakistan Journal of Ophthalmology, Volume 28, Issue 4.
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