Abstract
Purpose: To determine the clinical outcome of an Intravitreal Injection of Triamcinolone Acetonide in the treatment of Diabetic Macular Edema.
Material and Methods: The Study included 16 patients (32 eyes) who were diagnosed with clinical significant macular edema and treated with laser photocoagulation both grid and focal, received intravitreal triamcinolone acetonide injection 4mg/0.1ml under topical anaesthesia. The visual acuity was recorded before and after injection with 1 to 3 months of followup. Applanation tonometery was performed and readings recorded before and after injection.
Results: In this prospective study of 16 patients (32 eyes) with clinical significant macular edema (CSME) unresponsive to laser photocoagulation 11 patients were male (68.75%) and 5 female (31.25%) from 35 to 62 years of age, average age 52.25 years. Visual outcome after laser photocoagulation remained same in 19 eyes (59.37%), improved in 6 eyes (18.75%) and decreased in 7 eyes (21.87%). Visual outcome after intravitreal injection of triamcinolone acetonide improved in 18 eyes (56.25%) and remained same in 14 eyes (43.75%).
Conclusion: Intravitreal injection of 4mg/0.1ml triamcinolone acetonide may be beneficial for improving vision in patients with clinical significant macular edema (CSME) who are unresponsive to conventional laser photocoagulation.
Shahid Jamal Siddiqui, Syed Imtiaz Ali Shah, Muhammad Afzal Pechuho. (2009) Intravitreal Injection of Triamcinolone Acetonide for Diabetic Macular Edema, Pakistan Journal of Ophthalmology, Volume 25, Issue 3.
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