Abstract
The aim of the present study was to evaluate the antimicrobial potential including MIC of traditionally
used and ethnobotanically important tree Pterospermum acerifolium fruit. Laboratory isolates of six pathogenic
microorganisms, viz., Staphylococcus saprophyticus, Staphylococcus aureus, Escherichia coli, Pseudomonas
aeruginosa, Aspergillus parasiticus and Rhizopus oryzae, were used in the study for the evaluation of
antimicrobial activity. Fruit extracts prepared in different solvents demonstrated a varied level of broad spectrum
antimicrobial activity against all microbes. Among all the extracts used, chloroform extract showed maximum
antimicrobial activity in the form of zone of inhibition(mm) against P.aeruginosa (73.83±1.06mm) and R. oryzae
(84.6±0.7) followed by S. saprophyticus (71.36±1.00) and A. parasiticus (57.26±1.6), while minimum inhibitory
zone was observed by aqueous extract against E. coli (11.59±0.98) and S. aureus (16.43±1.20). Remaining
concentrates were likewise active and indicated microbial inhibition at different levels. Antimicrobial intensity was
compared with that of standard discs, like Amikacin, Kanamycin sulphate and Ketoconazole and was found
reasonably well
SHAZIA KANWAL MALIK, ZAHEER-UD-DIN KHAN, FARAH KHAN. (2016) Investigation of in-vitro Antimicrobial activity of Pterospermum acerifolium Linn. Fruit, Biologia – Journal of Biological Society of Pakistan, Volume 62 (I), Issue 1.
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