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Objective: To study the frequency of gallstone disease in patients with hepatitis C virus infection.
Study Design: Descriptive cross sectional study design.
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Place and Duration of Study: From 1 March 2019 to, 31 December 2019 at Department of Medicine and
Radiology of Pakistan Railway Hospital Rawalpindi
Materials and Methods: A total of 200 subjects were selected through non probability consecutive sampling
from medical In-patient and Out-patient Department. They were screened for hepatitis C virus (HCV) infection
by anti-HCV antibodies test by enzyme linked immunosorbant essay (ELISA). They were divided into two
groups. HCV positive and HCV negative groups with 100 participants in each group. The study subjects were
sent to Radiology Department for detection of gall stones by abdominal ultrasound. The data was obtained
from each participant regarding demographic and clinical variables and analyzed using SPSS version21.
Results: HCV positive patients had significantly higher frequency of gallstones (12.5%) compared with HCV
negative patients (4.5%). Higher percentage of males had gallstones in HCV positive group. Cirrhosis was
present in 52% of HCV infected patients.
Conclusion: The HCV infection is associated with increased risk of gallstone disease.
Samia Kausar, Fazeela Farid, Shamaila Burney, Kiran Fatima, Muhammad Farooq, Amina Shahzad. (2020) Hepatitis C Virus Infection, A Risk Factor for Gallstone Disease: A Cross Sectional Survey, Journal of Islamic International Medical College, Volume-15, Issue-2.
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