تلخیص
Viridans group streptococci (VGS), normal inhabitant of oral cavity, are involved in a number of oral and extra-oral diseases. Among oral diseases, dental caries is the most common public health problem throughout the world for all age groups. In the present study, the preliminary screening and minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests were conducted by well diffusion and tube dilution methods. Overall, clove buds (Eugenia caryophyllata) have potential to show strong antibacterial activities against tested VGS as compared miswak (root bark of Salvadora persica). The highest antibacterial activity was noted for clove oil as all the isolates were found susceptible. It exhibited strong antibacterial activity against Streptococcus mutans (20.2mm mean zone of inhibition±3.4SD) from carious subjects and S. sanguinis (17.7mm mean zone of inhibition ±1.1SD) from non-carious subjects. The aqueous decoction of clove buds was next to clove oil, exhibited the highest zone of inhibition against S. mutans obtained from carious subjects (16.8mm±3.4SD) followed by non-carious subjects (14.3mm±2.3SD). The aqueous infusion of clove buds showed the highest zone of inhibition against S. mutans isolated from carious (13.2mm±3.2SD) and non-carious (13.6mm±4.2SD) subjects. Aqueous infusion and aqueous decoction of miswak failed to inhibit the tested VGS. The MICs and MBCs of the clove oil, aqueous infusion and decoction of buds of clove against VGS was recorded as 5 – 0.625%, 5% and 5 – 2.5%, respectively.