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Pathogenesis of atherosclerosis involves mainly the inflammatory processes. In this regard, the degree of inflammation especially in coronary heart disease (CHD) and other ischemic disorders is widely considered to be associated with the variations in C-reactive protein (CRP). However, precise correlation of age-related high sensitivity CRP (hs-CRP) levels with the severity of injury is not clearly known. Hence, we carried out present study in age-matched male adult patients with CHD and compared this data with the normal male healthy adult control subjects (C). The results showed that aging increases the hs-CRP levels with significant positive linear correlation in patients with CHD as well as healthy control subjects. However, highly significant age-based increase of hs-CRP (mg/L) in CHD patients as compared to C subjects revealed the role of inflammation via change in hs-CRP. Conclusively, we investigated the involvement of hs-CRP in male adult patients with CHD, and suggest that the inflammation seems a major factor causing atherosclerotic conditions in CHD
Abdulhalim S. Seraf, Mohammed A. Bafail, M. H. Hussain, M. H. Hussain, Zahir Hussain. (2021) SERUM HIGH SENSITIVE C-REACTIVE PROTEIN (hs-CRP) IN MALE PATIENTS WITH CORONARY HEART DISEASE, , Volume 18, Issue 3.
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