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Emergence of multidrug-resistant (MDR) bacteria has become a global problem because infections due to MDR are hard to treat due to resistance to two or more classes of drugs, limiting the therapeutic options. The present study was undertaken to analyze the susceptibility pattern of Acinetobactor baumannii (A. baumanni) isolated from January 2016 to December 2020. The isolates were tested for the susceptibility to ceftazidime, imipenem, meropenem, amikacin, gentamicin, ciprofloxacin, co-trimoxazole, piperacillin/ tazobactam, and colistin by standard disc diffusion technique and assessed according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. A total of 1332 A. baumannii isolates were collected which were mostly retrieved from blood samples (29.3%). The frequency of multidrug resistance (MDR) was 69.4%. Overall the high resistance was observed for Co-trimoxazole and Ceftazidime (77%), followed by Fluoroquinolones (74%), Piperacillin/tazobactam (73%), Carbapenem (73%), Amikacin (66.6%), and Gentamycin (65%). In contrast, only 1.2% of the tested isolates were resistant to colistin. Increase in resistance against commonly used antibiotics were alarmingly high. Our data accentuate the need for comprehensive national control programs to control antibiotic resistance and to adopt the best therapeutic option for A. baumanni infections.

Nazia Khursheed, Qurat-ul-Ain, Maria Mushtaq Ali, Fareeha Adnan. (2021) ANTIMICROBIAL SUSCEPTIBILITY PATTERN AND EMERGING ANTIBIOGRAM TREND OF ACINETOBACTER BAUMANNII ISOLATES FROM A TERTIARY CARE HOSPITAL, , Volume 18, Issue 4.
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