تلخیص
The objective of this study was to assess the antihyperlipidemic efficacy of cinnamon powder in
albino rats. For this purpose 180 adult albino rats (average weight 210 ± 11 grams) were purchased
and divided into six groups. In rats blood lipid profile was raised using cholesterol @ 400mg/Kg body
weight of rat which was mixed into rat feed for first 15 days of the study. Cinnamon bark powder
equivalent to 1gm/kg, 2gm/kg, 4gm/kg and 6gm/kg was administered to the rats of treatment groups
15-60 days. Treatment control group was given Simvastatin at the dose rate of 0.6mg/Kg body
weight. Blood samples were collected at 0, 15, 30, 45 and 60 days in sterilized gel tubes by direct
heart puncturing. Serum was separated and analyzed for lipid profile parameters using reagent kits.
Findings of present study revealed that various doses of Cinnamomum cassiae powder improved the
serum lipid profile in albino rats by reducing Total Lipids, Total Cholesterol, Triglycerides and LDL
cholesterol and increasing HDL cholesterol levels in cinnamon treated groups. Furthermore, the most
significant effect was shown by 6 mg/kg dose level. From the results of the present study, it was
concluded that Cinnamon powder has curative effect against hyperlipidemia.
Zahid Iqbal, Taseer Ashraf, Aamir Ali Khan, Riaz Hussain, Mohiuddin Mudassar. (2016) ANTIHYPERLIPIDEMIC EFFICACY OF CINNAMON IN ALBINO RATS, Asian Journal of Agriculture and Biology, Volume 4, Issue 1.
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