Hydatid cyst is a occasional source of sudden death, with only a few cases being reported in the clinical literature. The purpose of this study is to present a rare case of hydatid infection in woman complaining pain in thighs and suspecting osteomyelitis/tuberculosis. The X-ray revealed that the patient had cystic lesion. The removed lesion was sent to Aga Khan Laboratory for histopathological evaluation where on microscopy it was found to be hydatid cysts of bone of various sizes. Histopathological study of bone presented a homogeneous necrotic area, situated on generalized dystrophic background.