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The study conducted as a cross-sectional to include 62 Saudi diabetic patients admitted to intensive-care unit (ICU) with silent cardiac symptoms; 39 of them had MI and 23 had other cardiac disease. The control group involved 40 healthy patients. Blood samples were taken from participants at the moment they were hospitalized in ICU to determine CK-MB, homocysteine, troponin I (cTnI), N-terminal pro-atrial natriuretic peptide (NT-proANP) and pentraxin (PTX3) using ELISA methods. NT-proANP levels showed a significant high increase in the MI patient compared to the control and non-MI patients. Such raised levels were also found in the results of CK-MB, cTnI and homocysteine. While PTX3 levels in non-MI patients showed insignificant elevation comparing to the control. Not like the routine cardiac markers, both serum NT-proANP and PTX3 levels were insignificantly changed in MI male and MI female patients. In conclusion, all patients admitted to ICU showed significant increase in the routine markers, whereas NT-proANP and PTX3 were independent risk factors in the onset of MI.
Kamal-Eldin Ahmed Abdelsalam. (2019) SERUM NT- PRO-ATRIAL NATRIURETIC PEPTIDE AND PENTRAXIN 3 AS COMPARATIVE TO ROUTINE CARDIAC FUNCTIONS TESTS IN DIABETIC PATIENTS WITH MYOCARDIAL INFARCTION, , Volume 16, Issue 3.
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