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The present study was designed to provide additional information on the effects of smoking on cardiac function tests with serum lipid profile. As a cross-sectional case-control, this study was designed to include 50 healthy and nonsmoking young males and 50 young smokers. All participants were in age and body-mass-index matched. After informed consent was taken, blood was collected in fasting status to determine serum cardiac markers along with lipid profile. The results of smokers comparing to non-smoker group showed insignificant reduction in cardiac Troponin I [cTnI] (p  0.05), but a significant rise in creatine kinase [CK-MB], C-reactive protein [CRP], homocysteine [Hyc] (p  0.001). Moreover, the lipid results showed that only total cholesterol was increased significantly in smokers (p  0.001) although the other lipid results were insignificantly changed in the serum of smokers. All these results, especially, the low cTnI level with high CK-MB and high cholesterol with normal HDL could not serve as a predictive or prognostic index for cardiac evaluation, and still it is not clear by which mechanism smoking exerts its detrimental effects on cardiovascular disease.

Kamal-Eldin Ahmed Abdelsalam. (2019) EFFECTS OF SMOKING ON CARDIAC FUNCTION TESTS AMONG MALE SAUDI YOUNGSTERS, , Volume 16, Issue 3.
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