تلخیص
The present study was designed to provide additional information on the effects of smoking on cardiac function tests with serum lipid profile. As a cross-sectional case-control, this study was designed to include 50 healthy and nonsmoking young males and 50 young smokers. All participants were in age and body-mass-index matched. After informed consent was taken, blood was collected in fasting status to determine serum cardiac markers along with lipid profile. The results of smokers comparing to non-smoker group showed insignificant reduction in cardiac Troponin I [cTnI] (p 0.05), but a significant rise in creatine kinase [CK-MB], C-reactive protein [CRP], homocysteine [Hyc] (p 0.001). Moreover, the lipid results showed that only total cholesterol was increased significantly in smokers (p 0.001) although the other lipid results were insignificantly changed in the serum of smokers. All these results, especially, the low cTnI level with high CK-MB and high cholesterol with normal HDL could not serve as a predictive or prognostic index for cardiac evaluation, and still it is not clear by which mechanism smoking exerts its detrimental effects on cardiovascular disease.