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In athletes with Type 2 Diabetes Mellitus, exercise regiments are very important, as minor deviation could cause release of biochemical radicals and lactate over-production. Therefore proper exercise, viz aerobic, resistance or combined is suggested to help in control of glycemia in T2DM patients. Present study reports the assessment of blood lactate concentrations in athletes with controlled type 2 diabetes mellitus, who exercise regularly. Post-exercise 1 h level of lactate was high, 21.4 ± 12.55 (P < 0.05), which was gradually decreased and significantly normalized to 3.15 ± 1.10 (P < 0.001) mg/L within 6 h. Enzymes LDH and CK/CPK also normalized gradually within 6 h (P < 0.05) in addition to glucose levels which declined from 110 mg/dL (post 1h) to level of 85 mg/dL (post 6 h P < 0.05). It was concluded that for muscle activity and oxidative metabolism in T2DM athletic individuals, regular exercise regulates glycemic control by increasing intermittent lactate concentration and activates antioxidant enzymes, which consequently controls reduction of Reactive oxygen species (ROS) production such minimizing muscle and cellular damages.
Humayun Imran Azeemi, Basit Ansari, Junaid Mahmood Alam, Syed Riaz Mahmood. (2019) ASSESSMENT OF BLOOD LACTATE LEVELS AND ITS CORRELATION WITH STRENUOUS EXERCISE IN MALE ATHLETES WITH TYPE 2 DIABETES MELLITUS (T2DM), , Volume 16, Issue 2.
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