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Background:Malnutrition in hospitalized patients, contributes to poor outcomes. Biomarkerserum prealbumin, can prevent thecomplicationsby commencement of nutritional support to improveclinical outcomes. This study was designed to assess the association between low serum prealbumin level (<18mg/dl), with length of stay and all cause intensive care unit mortality.Methods:Thiscross-sectional study was conducted from July 2016 to July 2017 at Aga Khan University Hospital Karachi Pakistan. All consecutive patients, aged between 18 to 70 years,admitted in medical or surgical intensive care unit were included. Demographic, clinical history and blood samples for analysingserum prealbuminwere obtained on first day of admission. Patients were categorized into two groups based on their serum prealbumin level (taking <18 mg/dl as low).Results: A total of 139 patients were included in this study;95 (68.3%) were male. Median (Q3-Q1) prealbumin level of 12.3 mg/dl (18.8–8.7) was observed with low prealbumin level (<18 mg/dl) in 100(71.9%) patients. All-cause mortality was observed in 26 (26.0%) patients, mortality rate was significantly higher in patients with low prealbuminlevel (26.0% vs. 17.9%), p-value =0.31). Hospital and intensive care unit length of stay were statistically insignificantly different between the two groups with p-values of 0.27 and 0.44respectively.Conclusion:We did not find association of lowserum prealbumin with length of stay andmortality.Further research is warranted for the assessment of prealbuminas independent predictor of ICU mortality.
Aysha Habib Khan, , afsa Majid, Lena Jafri, Bushra Akram††, , Ahmed Raheem, Bushra Jamil, Madiha Hashmi, Aysha Habib Khan. (2019) ASSESSING NUTRITIONAL STATUS OF CRITICALLY ILL PATIENTS USING SERUM PREALBUMIN LEVELS, JOURNAL OF AYUB MEDICAL COLLEGE ABBOTTABAD, Volume 31, Issue 2.
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