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The foetus acquires rubella through the course of pregnancy. The clinical significance depends on the time of the mother's acquisition of the virus. If maternal infection happens to be in the first trimester, the risk of rubella-associated defects is greatly increased. According to Pumper and Yamashiroya, between 50% and 80% of foetuses exposed to maternal rubella virus become infected prior to the 8th weeks of gestation. Infection of the foetus is fairly uncommon, during the 3rdtrimester which is 6–10%. The eyes, the ears, the heart, the central nervous system and the brain appear tobe especially susceptible to rubella-associated damage.1Aniridia is the absence of iris, has rarely been described in literature in association with CRS. It is a rare association which can easily be overlooked, and can lead to complications e.g. glaucoma and blindness later in life.We report the case of a neonate with CRS and aniridia presenting at a tertiary care hospital – the first of its kind reported in literature.
Syed Rehan Ali,, Syed Rehan Ali, ,Nadia Mohammad, , Nabiha Ali, Shakeel Ahmed, Tauseef Ahmad. (2019) ANIRIDIA: A RARE MANIFESTATION OF CONGENITAL RUBELLA SYNDROME, JOURNAL OF AYUB MEDICAL COLLEGE ABBOTTABAD, Volume 31, Issue 1.
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