Abstract
Male adult albino Wistar rats (n=30), aged 10-12 weeks and weighing 180-200g of weight were divided in two equal
groups. Group-A (control), received no intervention and Group-B received single dose of 20mg/kg of methotrexate (MTX)
intraperitoneally. Liver was harvested and its architecture was assessed microscopically. Mean hepatocyte count, hepatocyte diameter
and hepatocyte nuclear diameter were calculated with micrometer
Tayyaba Kazmi, Nadia Younus, Asma Basharat Ali, Kishwer Sultana. (2020) Histo-morphometric changes in Methotrexate induced Hepatotoxicity in Albino rat, Isra Medical Journal, Volume 12, Issue 4.
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