Abstract
Background: Chronic usage of diacetylmorphine has significant impact on different physiological
processes of the body. Haematological parameters are reported to alter in diacetylmorphine addiction
leading mainly to various signs and symptoms of anaemia and infection. This study was designed to
investigate for haematological and immunological parameters in diacetylmorphine (heroin) addicts.
Methods: This was a case control study. We recruited forty-one male heroin addicts aged 25–46 years
along with forty-one male healthy subjects as controls. The subjects were assessed clinically through
history and physical examination. Complete blood count (CBC) was done by Celldyne Ruby,
Multiparameter Automated Haematology Analyser. Data was presented as Mean±SD. Independent
sample t-test was used to compare differences between the two groups on SPSS-22, and p<0.05 was
considered significant. Results: There were decreased haemoglobin levels, haematocrit, mean
corpuscular volume, mean corpuscular haemoglobin concentration (p<0.01) and marginal increase in
WBC count in diacetylmorphine addicts. Rest of the haematological parameters were normal.
Conclusion: Diacetylmorphine addiction showed significant changes in haematological parameters
compared to control group.
Syeda Huma Khizar, Syed Hamid Habib, Muhammad Omar Malik, Sahar Farhat, Safia Bibi, Qazi Muhammed Qasim. (2020) HAEMATOLOGICAL AND IMMUNOLOGICAL PARAMETERS AMONG DIACETYLMORPHINE ADDICTS, Pakistan Journal of Physiology, Volume 16, Issue 2.
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