Abstract
Natural bioactive molecules or compounds isolated from different living organisms
are the rich sources for the novel drugs. Endophytes are the rich source of these bioactive
molecules having a wide range of applications as compared to the original products. Fungal
endophytes are the most commonly used endophytes for the isolation of various different types
of bioactive molecules. These bioactive molecules can be used as antimicrobial, antibacterial and
anticancer agents. Fungal endophytes like Taxomyces andreanae isolated from Yew plant have
the potential to produce an anti-cancer compound called Paclitaxel. Other different fungal
endophytic species produce various other types of anticancer compounds like camptothecin,
podophyllotoxin, torreyanic acid, vincristine, and vinblastine. This review is organized to
describe the general study of natural bioactive molecules or secondary metabolites secreted by
fungal endophytes as novel sources of anticancer drugs. The main purpose of this review is to
organize the effective compound of the fungal endophytes for cancer treatments.
Mohammad Ejaz, Salma Javed, Muhammad Hamza, Sadia Tabassum, Muhammad Abubakar, Irfan Ullah. (2020) Fungal Endophytes are Effective Alternatives and Novel Sources of Anticancer Drugs, Punjab University Journal of Zoology, Volume 35, Issue 1.
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