Abstract
Objective: To find out the frequency of non-adherence in patients with anxiety and depression, receiving
treatment in teaching hospitals.
Study Design:A cross-sectional descriptive study
Place and Duration of Study: The study was conducted at Pakistan Railway Hospital, Rawalpindi and Riphah
st st
International Hospital, Islamabad from1 June 2018 to 31 December 2018.
Materials and Methods: After approval from Ethics review committee (ERC) and informed consent of the
participants, those meeting inclusion criteria; 310 patients (n=310) were included in this study. Out of these
151(n=151) patients were suffering from depression, while 159(n=159) were having anxiety. Patients with
mixed anxiety and depression were excluded. Demographic details (age, gender, education, marital status)
were recorded. International classifications of diseases (ICD-10) diagnostic guidelines and clinical assessment
was used to confirm diagnosis of anxiety and depression. The Morisky Medication Adherence Scale (MMAS-8)
was used to measure levels of non-adherence. Data was analyzed using SPSS-20 and results compiled
accordingly.
Results: Out of 151(n=151) depressed patients 81.4% have low to medium adherence to pharmacological
treatment, while out of 159(n=159), patients with anxiety 78% have medium to low adherence to prescribed
treatment. Medication non-adherence was statistically significant in both anxious and depressed patients.
Conclusion: Patients suffering from anxiety and depression show significant non- adherence to
pharmacological treatment.
Masood Khokhar, Shafaq Masood, Ather Muneer, Uzzama Waheed, Farwa Aftab, Irum Bibi. (2020) Medication Non-Adherence in Anxiety and Depression, Journal of Islamic International Medical College, Volume-15, Issue-1.
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