Abstract
Objective: Objective of the study is to see the Co-relation in between ALT and viral load of HBV positive
individuals in a tertiary care facility of Rawalpindi.
Study Design: This was a cross sectional study using facility based data of diagnosed and treated patients.
Place and Duration of Study: Study was conducted during the first six months of 2019 from first January to 30th
June at liver center Holy family Hospital.
Materials and Methods: This was a cross sectional study carried out in a tertiary level care facility of
Rawalpindi, the duration of the study was from January 2019 to June 2019. All patients with HBV positive and
age above 18 years investigated admitted recorded followed up from January 2019 to June 2019 were included.
Sampling method was Non-probability universal sampling. Data was collected through questionnaire
mentioning all the required variables. Data was entered and analyzed by using Statistical package for social
sciences version 21 for frequencies cross tabulations and co relation.
Results: Co-relation was checked in between the ALT and viral load. It was observed that apparently there is no
co relation in between the ALT and the amount of viral load. Statistically there is slightly negative correlation in
between the ALT and the viral load and even it can be said no co-relation
Conclusion: ALT is not the true representative of viral load in hepatitis B. A low ALT can present with high viral
load and high ALT can be found with low viral load. Therefore the treatment and prognostic models should not
be only relied upon ALT as commonly done by the general practitioners.
Hammad Ayaz, Huma Mahmood Mughal, Muhammad Ayaz Bhatti. (2019) Viral Load and Alanine Amino Transferase (ALT) in Hepatitis B Positive Individuals at a Tertiary Level Care Hospital, Journal of Islamic International Medical College, Volume-14, Issue-4.
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