Abstract
Objective To evaluate the effectiveness and safety of early Nasogastric Enteral Nutrition in patients with Acute
pancreatitis
Study Des ign Randomized controlled trial.
Place and Duration of Study: The study was conducted at IIMC Hospital Islamabad, and Railways Hospital
Rawalpindi from June 2008 toApril 2011 _
Materials and Methods: A total of 26 patients were studied over the course of 34 months who were admitted
with the diagnosis of acute pancreatitis, Patients were divided randomly in two equal groups by consecutive
sampling method. One group was given enteral nutrition (EN) through nasogastric tube beginning within 24
hours of admission (group-I), and the other group was provided nutrition through parenteral route (PN) only
(Group-II). Outcome In the two groups such as length of hospital and ICIJ stay, infective complications, nutrition
related complications. metabolic and catheter related complications were compared.
Results: Baseline of the study regarding infective complications and mortality were comparable. Average
hospital stay was shorter by 22.3% in enterally fed group. ICIJ stay was also shorter in group-I patients.
Significant difference was seen in relief of abdominal pain amongst the two groups. enterally fed (group-I)
patients had earlier relief of pain starting on the 3rd day, compared to 5m day in group-II. Majority of the patients in
group-I (84.5%) hadpain relief between 4" and9th day, while in group-II, 76.8% had pain relief between 7" and 1 2m
day. Mean pain relief in enterally fed patients was in 7.5 days and in parenteral nutrition group in 10.2 days.
Nutrition related complication of diarrhoea was noted in 2 enterally fed patients. Metabolic complications
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(hyperglycaemia), and catheter related septic complications were seen only in parenterally fed patients. Acute
pseudocystformation occurred in one patient of enterally fed group as noted on follow up.
Conclusion: Early enteral nutrition is safe and effective in the management of acute pancreatitis. Enterally fed
patients show advantage Of shorter hospital and ICU stay, and earlier relief of symptoms compared to patients
managed on parenteral nutrition. Our study considers early enteral nutrition feasible and desirable.
Ahmed Nurus Sami, Naseer Khan, Hamid Rasheed Goreja. (2013) Early Nasogastric Enteral Nutrition in Acute Pancreatitis, Journal of Islamic International Medical College, Volume-8, Issue-1.
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