Abstract
Objective: To evaluate the prevalence of certain
microorganisms in urine and their antibiotic
sensitivities.
Keywords: Antibiotics, Antimicrobial Drug
Resistance, Bacteriuria, Cystitis, Gram Negative
Bacteria, Gram Positive Bacteria, Urinary Tract
Infections.
Results: Mean age of patients was 59.49years
(range 1-90). A total of 290 reports yielded 319
microorganisms among which 29 reports showed
two organisms each. Candida spp. co-existed in 26
cases. E.coli was found to be the most prevalent
organism; 181/319 (56.74%), followed by
Enterococcus faecalis; 58/319 (18.18%). Most
active antibiotics against gram positive organisms
were; Linezolid (100%, n=58), Doxycycline
(96.55%, n=58), Vancomycin (91.22%, n=57) and
Nitrofurantoin (70.68%). Most efficient antibiotics
against gram negative organisms were; Fosfomycin
(90.91%, n=198), Carbapenems i.e. Imipenem and
Meropenem (89.19%, n=259), Amikacin (85.6%,
n=250), Cefoperazone plus Sulbactam (81.62%,
n=234), Piperacillin plus Tazobactam (80.54%,
n=257) and Nitrofurantoin (72.88%).
Conclusion: E.coli was the most prevalent
organism and Fosfomycin and Carbapenems
were most effective antibiotics. Fluoroquinolones
didn't appear to be a good choice for treatment of
UTIs. (Rawal Med J 202;45:22-26)
