Abstract
Objective: To evaluate the prevalence of certain microorganisms in urine and their antibiotic sensitivities. Keywords: Antibiotics, Antimicrobial Drug Resistance, Bacteriuria, Cystitis, Gram Negative Bacteria, Gram Positive Bacteria, Urinary Tract Infections. Results: Mean age of patients was 59.49years (range 1-90). A total of 290 reports yielded 319 microorganisms among which 29 reports showed two organisms each. Candida spp. co-existed in 26 cases. E.coli was found to be the most prevalent organism; 181/319 (56.74%), followed by Enterococcus faecalis; 58/319 (18.18%). Most active antibiotics against gram positive organisms were; Linezolid (100%, n=58), Doxycycline (96.55%, n=58), Vancomycin (91.22%, n=57) and Nitrofurantoin (70.68%). Most efficient antibiotics against gram negative organisms were; Fosfomycin (90.91%, n=198), Carbapenems i.e. Imipenem and Meropenem (89.19%, n=259), Amikacin (85.6%, n=250), Cefoperazone plus Sulbactam (81.62%, n=234), Piperacillin plus Tazobactam (80.54%, n=257) and Nitrofurantoin (72.88%). Conclusion: E.coli was the most prevalent organism and Fosfomycin and Carbapenems were most effective antibiotics. Fluoroquinolones didn't appear to be a good choice for treatment of UTIs. (Rawal Med J 202;45:22-26)

Salman Farooq Dar, Malik Muhammad Atif, Muhammad Hamza Arshad, Muhammad Fahr Hayat, Talha Farooq Dar. (2020) Urinary tract pathogens and their patterns of resistance to commonly used antibiotics, , Volume 45, Issue-1.
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