Abstract
Experiments conducted in different model systems show that gene therapy can extend the life span of an organism.
Various genetic interventions, which include mutation, knockout, and overexpression, led to the extension of life span
in Caenorhabditis, Drosophila melanogaster, mouse, yeast, and even human cell lines. Our literature review revealed
that few aging theories could be used as an excellent tool to increase longevity, and delay aging in an organism. In this
review, we have provided a brief view of the majority of genetic therapies done on model organisms from 1980 to 2018
as an anti-aging treatment.
